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SBP0012 - Pep2-SVKI




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Description

SBP0012 - Pep2-SVKI
MW: 1284.47
H-Tyr-Asn-Val-Tyr-Gly-Ile-Glu-Ser-Val-Lys-Ile-OH
Inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluR2 AMPA receptor subunit. Disrupts binding of the GluR2 (at the C-terminal PDZ site) with glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP) and protein interacting with C kinase (PICK1). Increases amplitude of AMPA receptor mediated currents and blocks long-term depression (LTD).
Li et al (1999) Nature.Neurosci. 2 972.
1mg
5mg