0 Items  |   £0.00
T: +44 (0)1562 825286       E: info@SevernBiotech.com

 

 
 

SBP0087 - Urocortin, human




Add to Cart:


*NOT ALL PRICES ARE CORRECT. PLEASE CHECK WITH SEVERN BIOTECH SALES OFFICE PRIOR TO PURCHASE
+44 (0)1562 825286*


.

 
Description

SBP0087 - Urocortin, human
MW: 4696.8
H-Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2
Following the discovery of urocortin in rat brain, the human peptide was cloned. Human and rat urocortin show 95% sequence homology. Human urocortin has been shown to bind to CRF-1, CRF-2alpha and CRF-2beta receptors as well as CRF-BP. Urocortin is reported to be more effective at suppressing appetite than CRF, but less potent at producing anxiety-like effects.
Donaldson et al. (1996), Endocrinology 137, 2167; Spina et al. (1996) Science 273, 1561.
500µg
1mg